| Class A | Class AA |
| Sectional A |
Host: Beecher @ Beecher Softball Field, 690 Hodges Street, Beecher -  |
| Streator St. Anthony (9-3) vs. Beecher (22-1) |
| Regional 1 | Streator St. Anthony def. Waterman Indian Creek, 7-6 |
| Regional 2 | Beecher def. Lockport Kelvin Grove, 9-1 |
| Sectional B |
| Host: Pontiac St. Mary's @ Pontiac Rec-Plex, 1200 S. Old Airport Road, Pontiac - |
| Pontiac St. Mary's (7-2) vs. Champaign St. Matthew (10-6) |
| Regional 3 | Pontiac St. Mary's def. Flanagan, 12-2 |
| Regional 4 | Champaign St. Matthew def. St. Anne, 15-9 |
| Sectional C |
| Host: Metamora St. Mary's @ Metamora Township High School, 101 W Madison, Metamora - |
| Henry-Senachwine (9-6) vs. Metamora St. Mary's (18-3) |
| Regional 5 | Henry-Senachwine def. Sparland Midland, 7-5 |
| Regional 6 | Metamora St. Mary's def. Peoria Christian, 10-3 |
| Sectional D |
| Host: Delavan @ Gardner Field, 100 N Locust St, Delavan - |
| Glasford Illini Bluffs (19-2) vs. Hartsburg-Emden (10-4) |
| Regional 7 | Glasford Illini Bluffs def. Havana, 5-0 |
| Regional 8 | Hartsburg-Emden def. Tremont, 6-3 |
| Sectional E |
| Host: Virginia @ Dunaway Park, 701 S. Morgan, Virginia - |
| Springfield St. Agnes (14-8) vs. New Berlin JHS (14-1) |
| Regional 9 | Springfield St. Agnes def. Springfield Calvary, 15-2 |
| Regional 10 | New Berlin JHS def. Chandlerville A-C Central, 5-0 |
| Sectional F |
| Host: Carrollton St. John |
| Griggsville-Perry (12-1) vs. Winchester (13-4) |
| Regional 11 | Griggsville-Perry def. Payson Seymour, 8-6 |
| Regional 12 | Winchester def. Carrollton St. John, 11-1 |
| Sectional G |
| Host: Pawnee @ Pawnee, 810 4th Street, Pawnee - |
| Pawnee (6-2) vs. Raymond Lincolnwood (11-4) |
| Regional 13 | Pawnee def. Buffalo Tri-City, 5-2 |
| Regional 14 | Raymond Lincolnwood def. Altamont, 7-0 |
| Sectional H |
| Host: Effingham St. Anthony |
| Effingham St. Anthony (11-4) vs. Toledo Cumberland (18-5) |
| Regional 15 | Effingham St. Anthony def. Newton St. Thomas, 12-8 |
| Regional 16 | Toledo Cumberland def. Oblong, 5-1 |
