| Class 1A | Class 2A | Class 3A |
| Sectional A |
@ A. Vito Martinez Middle School, 590 Belmont Drive, Romeoville -  |
| Glendale Heights Glenside (7-5) vs. Romeoville Martinez (16-3) |
| Regional 1 | Glendale Heights Glenside def. Schiller Park Lincoln, 4-2 |
| Regional 2 | Romeoville Martinez def. Romeoville Lukancic, 7-4 |
| Sectional B |
| @ Minooka |
| Wenona Fieldcrest (12-0) vs. Minooka (21-1) |
| Regional 3 | Wenona Fieldcrest def. Coal City, 11-3 |
| Regional 4 | Minooka def. Braidwood Reed-Custer, 11-1 |
| Sectional C |
| @ Bourbonnais UGC |
| Homer Glen Homer (13-4) vs. Bourbonnais UGC (8-5) |
| Regional 5 | Homer Glen Homer def. Lockport Oak Prairie, 8-3 |
| Regional 6 | Bourbonnais UGC def. Kankakee JHS, 5-4 |
| Sectional D |
| @ East Peoria Central |
| Pekin Edison (8-7) vs. East Peoria Central (22-2) |
| Regional 7 | Pekin Edison def. Canton Ingersoll, 12-6 |
| Regional 8 | East Peoria Central def. Morton JHS, 11-2 |
| Sectional E |
| @ Paxton-Buckley-Loda |
| Normal Chiddix (13-6) vs. Danville North Ridge (11-0) |
| Regional 9 | Normal Chiddix def. Normal Kingsley, 12-2 |
| Regional 10 | Danville North Ridge def. Danville South View, 8-3 |
| Sectional F |
| @ Medora Athletic Complex, 1 Mile North of Medora on Hwy. 267, Medora - |
| Pleasant Plains (15-2) vs. Piasa Southwestern (12-2) |
| Regional 11 | Pleasant Plains def. Chatham Glenwood, 3-2 |
| Regional 12 | Piasa Southwestern def. Greenville, 5-2 |
| Sectional G |
| @ Stanford Olympia |
| Minier Park, Minier, IL |
| Stanford Olympia (11-1) vs. Rochester (17-2) |
| Regional 13 | Stanford Olympia def. Normal Parkside, 6-4 |
| Regional 14 | Rochester def. Riverton, 13-3 |
| Sectional H |
| @ Casey-Westfield |
| Charleston (11-3) vs. Effingham JHS (14-8) |
| Regional 15 | Charleston def. Mt. Zion, 5-4 |
| Regional 16 | Effingham JHS def. Teutopolis, 6-3 |
