| Sectional 1 @ Bolingbrook Jane Addams |
| Bellwood Roosevelt (19-1) vs. Bolingbrook Jane Addams (14-6) |
| Regional 1 | Bellwood Roosevelt def. Arlington Heights South, 52-49 (OT) |
| Regional 2 | Bolingbrook Jane Addams def. Bolingbrook Brooks, 50-47 |
| Sectional 2 @ Calumet City Schrum |
| Harvey Brooks (16-1) vs. Calumet City Schrum (18-0) |
| Regional 3 | Harvey Brooks def. Dolton Roosevelt, 60-34 |
| Regional 4 | Calumet City Schrum def. Calumet City Lincoln, 55-34 |
| Sectional 3 @ Manteno |
| Country Club Hills Southwood (17-1) vs. Park Forest Forest Trail (18-0) |
| Regional 5 | Country Club Hills Southwood def. Markham Prairie-Hills, 57-46 |
| Regional 6 | Park Forest Forest Trail def. Ford Heights Cottage Grove, 50-39 |
| Sectional 4 @ Homer Glen Homer |
| Homer Glen Homer (15-7) vs. Joliet Hufford (13-6) |
| Regional 7 | Homer Glen Homer def. New Lenox Martino, 50-41 |
| Regional 8 | Joliet Hufford def. Joliet Washington, 46-39 |
| Sectional 5 @ Wilmington Stevens |
| Channahon (19-3) vs. Dwight (17-7) |
| Regional 9 | Channahon def. Wilmington Stevens, 27-24 |
| Regional 10 | Dwight def. Streator Northlawn, 52-35 |
| Sectional 6 @ Forrest Prairie Central |
| Bourbonnais UGC (15-5) vs. Gibson City GCMS (17-4) |
| Regional 11 | Bourbonnais UGC def. Kankakee JHS, 37-35 |
| Regional 12 | Gibson City GCMS def. Forrest Prairie Central, 28-27 |
| Sectional 7 @ Washington MS |
| Normal Kingsley (14-7) vs. Eureka (21-1) |
| Regional 13 | Normal Kingsley def. Normal Chiddix, 39-33 |
| Regional 14 | Eureka def. Washington Central, 32-29 |
| Sectional 8 @ Dunlap MS |
| Mossville (18-3) vs. Morton JHS (16-5) |
| Regional 15 | Mossville def. Dunlap MS, 38-34 |
| Regional 16 | Morton JHS def. East Peoria Central, 38-31 |
| Sectional 9 @ Farmington Central |
| Pekin Edison (12-5) vs. Sherrard JHS (17-3) |
| Regional 17 | Pekin Edison def. Canton Ingersoll, 53-40 |
| Regional 18 | Sherrard JHS def. Colchester West Prairie, 42-20 |
| Sectional 10 @ Champaign Edison |
| Danville North Ridge (13-7) vs. Champaign Edison (19-2) |
| Regional 19 | Danville North Ridge def. Westville JHS, 48-41 |
| Regional 20 | Champaign Edison def. Champaign Franklin, 43-29 |
| Sectional 11 @ Heyworth |
| Mahomet-Seymour (19-2) vs. Heyworth (22-0) |
| Regional 21 | Mahomet-Seymour def. Tolono Unity, 48-37 |
| Regional 22 | Heyworth def. Downs Tri-Valley, 61-28 |
| Sectional 12 @ Pittsfield Pikeland |
| Jacksonville Turner (20-2) vs. Quincy (16-5) |
| Regional 23 | Jacksonville Turner def. Petersburg PORTA JHS, 45-18 |
| Regional 24 | Quincy def. Pittsfield Pikeland, 44-33 |
| Sectional 13 @ Casey-Westfield |
| Mattoon vs. Robinson Nuttall (19-1) |
| Regional 25 | Mattoon def. Charleston, 37-24 |
| Regional 26 | Robinson Nuttall def. Teutopolis, 55-43 |
| Sectional 14 @ Blue Mound Meridian |
| Mt. Zion vs. Decatur Stephen Decatur (18-0) |
| Regional 27 | Mt. Zion def. Pana JHS, 38-22 |
| Regional 28 | Decatur Stephen Decatur def. Blue Mound Meridian, 62-44 |
| Sectional 15 @ Springfield Franklin |
| Springfield Jefferson (17-1) vs. Auburn (14-7) |
| Regional 29 | Springfield Jefferson def. Springfield Franklin, 37-36 |
| Regional 30 | Auburn def. Jerseyville Illini, 53-38 |
| Sectional 16 @ Vandalia |
| Edwardsville Liberty (17-4) vs. East St. Louis Clark (17-3) |
| Regional 31 | Edwardsville Liberty def. Staunton, 34-28 |
| Regional 32 | East St. Louis Clark def. Cahokia Wirth, 32-31 |
