| Sectional 1 @ Morris Saratoga |
| Seneca def. Chicago St. Malachy 44-38 |
Seneca record now 13-9 |
| Sectional 2 @ Grand Ridge |
| Tonica def. Streator St. Stephen 33-32 |
Tonica record now 15-9 |
| Sectional 3 @ Tri-Point JHS, Piper City |
| Gifford def. Milford 31-28 |
Gifford record now 13-9 |
| Sectional 4 @ Normal Epiphany |
| Normal Epiphany def. Odell 59-25 |
Normal Epiphany record now 22-1 |
| Sectional 5 @ Washington St. Patrick |
| Bartonville Monroe def. Sparland Midland 24-22 |
Bartonville Monroe record now 16-6 |
| Sectional 6 @ Cuba Middle School |
| Cuba def. Peoria Norwood 34-29 |
Cuba record now 12-8 |
| Sectional 7 @ Colchester West Prairie |
| Media Southern def. Hamilton 37-30 |
Media Southern record now 21-0 |
| Sectional 8 @ Catlin |
| Catlin def. Royal Prairieview 44-12 |
Catlin record now 19-1 |
| Sectional 9 @ G.C.M.S. MS, Gibson City |
| Champaign St. Matthew def. Rantoul St. Malachy 27-19 |
Champaign St. Matthew record now 20-3 |
| Sectional 10 @ Oakland Lake Crest |
| Paris Crestwood def. Tuscola East Prairie 29-20 |
Paris Crestwood record now 22-0 |
| Sectional 11 @ Central A & M MS, Assumption |
| Assumption Central A & M def. Decatur Johns Hill 39-15 |
Assumption Central A & M record now 18-4 |
| Sectional 12 @ Pawnee |
| Springfield Blessed Sacrament def. Pawnee 39-32 |
Springfield Blessed Sacrament record now 22-2 |
| Sectional 13 @ Virginia |
| Springfield St. Agnes def. Lincoln Chester-East Lincoln 34-32 |
Springfield St. Agnes record now 19-4 |
| Sectional 14 @ Brown County MS, Mt. Sterling |
| Winchester def. Griggsville-Perry 31-25 |
Winchester record now 16-6 |
| Sectional 15 @ St. Anthony GS, Effingham |
| Beecher City def. Noble West Richland 30-29 |
Beecher City record now 18-3 |
| Sectional 16 @ Greenfield High School, Greenfield |
| Greenfield def. Bunker Hill Meissner 45-13 |
Greenfield record now 19-0 |
