| Sectional 1 @ Richland GS, Crest Hill |
| Crest Hill Richland def. Beecher 34-18 |
Crest Hill Richland record now 13-5 |
| Sectional 2 @ Fieldcrest East MS, Wenona |
| Tonica def. Streator St. Stephen 35-27 |
Tonica record now 18-4 |
| Sectional 3 @ Tri-Point JHS, Piper City |
| Gifford def. Donovan 26-9 |
Gifford record now 15-5 |
| Sectional 4 @ Roanoke-Benson |
| Normal Epiphany def. Pontiac St. Mary's 29-26 |
Normal Epiphany record now 22-1 |
| Sectional 5 @ Washington St. Patrick |
| Peoria Pleasant Valley def. Mackinaw Dee-Mack 31-21 |
Peoria Pleasant Valley record now 17-3 |
| Sectional 6 @ Brimfield |
| Lewistown Central def. Brimfield 27-20 |
Lewistown Central record now 15-5 |
| Sectional 7 @ Biggsville Union |
| Colchester West Prairie def. Abingdon 28-26 |
Colchester West Prairie record now 14-10 |
| Sectional 8 @ Jamaica JHS, Sidell |
| Sidell Jamaica def. Potomac 28-25 |
Sidell Jamaica record now 15-3 |
| Sectional 9 @ Fisher |
| LeRoy def. Champaign St. Matthew 29-28 |
LeRoy record now 11-9 |
| Sectional 10 @ Oakland Lake Crest |
| Paris Crestwood def. Tuscola East Prairie 18-16 |
Paris Crestwood record now 15-4 |
| Sectional 11 @ Central A & M MS, Assumption |
| Assumption Central A & M def. Cerro Gordo 30-23 |
Assumption Central A & M record now 17-4 |
| Sectional 12 @ Divernon |
| Springfield Blessed Sacrament def. Nokomis JHS 47-38 |
Springfield Blessed Sacrament record now 19-4 |
| Sectional 13 @ A-C Central JHS, Chandlerville |
| Springfield St. Agnes def. Mt. Pulaski 38-13 |
Springfield St. Agnes record now 16-5 |
| Sectional 14 @ Brown County MS, Mt. Sterling |
| Winchester def. Mendon Unity 29-22 |
Winchester record now 18-3 |
| Sectional 15 @ St. Anthony GS, Effingham |
| Louisville North Clay def. Palestine 30-28 |
Louisville North Clay record now 14-5 |
| Sectional 16 @ Carrollton St. John |
| Bunker Hill Meissner def. Carrollton St. John 21-18 |
Bunker Hill Meissner record now 15-6 |
