| Sectional 1 @ Lansing Memorial |
| Markham Prairie-Hills def. Lansing Memorial 33-20 |
Markham Prairie-Hills record now 20-2 |
| Sectional 2 @ Homer Glen Homer |
| Bellwood Roosevelt def. Homer Glen Homer 52-26 |
Bellwood Roosevelt record now 15-1 |
| Sectional 3 @ Manteno |
| Frankfort Hickory Creek def. Bradley Central 37-24 |
Frankfort Hickory Creek record now 17-4 |
| Sectional 4 @ Mokena |
| Joliet Hufford def. New Lenox Martino 33-21 |
Joliet Hufford record now 15-2 |
| Sectional 5 @ Coal City |
| Coal City def. Ottawa Shepherd 30-23 |
Coal City record now 19-3 |
| Sectional 6 @ Forrest Prairie Central |
| Forrest Prairie Central def. Rantoul Eater 48-23 |
Forrest Prairie Central record now 20-3 |
| Sectional 7 @ Normal Chiddix |
| Normal Kingsley def. Downs Tri-Valley 36-29 |
Normal Kingsley record now 21-0 |
| Sectional 8 @ Morton JHS |
| Dunlap MS def. Metamora Germantown Hills 24-15 |
Dunlap MS record now 18-4 |
| Sectional 9 @ Farmington Central |
| Canton Ingersoll def. Pekin Edison 37-18 |
Canton Ingersoll record now 22-1 |
| Sectional 10 @ TBD |
| Champaign Franklin def. Danville Oakwood 35-20 |
Champaign Franklin record now 17-0 |
| Sectional 11 @ Blue Mound Meridian |
| Mattoon def. Blue Mound Meridian 35-28 |
Mattoon record now 15-8 |
| Sectional 12 @ Rochester |
| Warrensburg-Latham def. Taylorville JHS 37-31 |
Warrensburg-Latham record now 22-0 |
| Sectional 13 @ Carlinville |
| Chatham Glenwood def. Piasa Southwestern 31-26 |
Chatham Glenwood record now 15-4 |
| Sectional 14 @ Pittsfield Pikeland |
| Pleasant Plains def. Quincy 37-18 |
Pleasant Plains record now 19-3 |
| Sectional 15 @ Toledo Cumberland |
| Toledo Cumberland def. Altamont 48-34 |
Toledo Cumberland record now 20-0 |
| Sectional 16 @ Vandalia |
| Hillsboro def. Cahokia Wirth 43-31 |
Hillsboro record now 22-0 |